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Appearance: | White Powder | CAS No.: | 378-44-9 |
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Standard: | USP, BP, EP | Other Name: | Betameth,Betasolon,Celestan,Celestone,Rinderon |
Type: | Antibiotic And Antimicrobial Agents |
Betameth/Betasolon/Celestan/Celestone/Betamethasone White powder CAS NO.378-44-9 Assay 99%
1.Product Name: Betamethasone
2.Other Names: Betameth,Betasolon,Celestan,Celestone,Rinderon
3.Type: Antibiotic and Antimicrobial Agents
4.Specification: 99%
5.Formula: C22H29FO5
6.Mol Wt.: 392.461
7.CAS No.: 378-44-9
8.EINECS No: 206-825-4.
9.Appearance: white powder..
Specification:
Standard: BP,EP, USP | ||
Test Item | Standard | Test Result |
Appearance | white crystal or powder | white crystal or powder |
Identification | infra-red spectrum | accord with normal frequency spectrum |
M.P. | 205°C-208°C | 206.4°C |
Specific rotation | +120°C-+128°C | +125.56°C |
Drying Loss | ≥4.0% | 2.18% |
Residue on Ignition | ≤0.2% | 0.12% |
Assay | 97.0%-103.0% |
99% |
Brief introduction:
Betamethasone is a potent glucocorticoid steroid with anti-inflammatory and immunosuppressiveproperties. Unlike other drugs with these effects, betamethasone does not cause water retention. It is applied as a topical cream, ointment, foam, lotion or gel to treat itching. Betamethasone sodium phosphate is sometimes prescribed as an intramuscular injection (I.M) for itching from various ailments, including allergic reactions to poison ivy and similar plants.
Indications:
Betamethasone is a corticosteroid used as a topical cream to relieve skin irritation, such as itching and flaking from eczema. It is used as a treatment for local psoriasis, as betamethasone dipropionate andsalicylic acid, or as the combination betamethasone/calcipotriol. Betamethasone sodium phosphate is used orally and via injection with the same indications as other steroids.
A cream with 0.05% betamethasone appears effective in treating phimosis in boys, and often averts the need for circumcision. It has replaced circumcision as the preferred treatment method for some physicians in theBritish National Health Service.
Betamethasone is also used to stimulate fetal lung maturation (prevention of IRDS), and to decrease the incidence and mortality from intracranial hemorrhage in premature infants.
As it crosses the placenta, which is required for its beneficial effects, it may also be associated with complications, such as hypoglycemia and leukocytosis in newborns exposed in utero.
Storage Situation:
Stored in a cool and dry well-closed container kept away from moisture and strong light or high temperature.
Shelf Life:
Two years under well Storage situation and stored away from direct sun light.
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